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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCL2 All Species: 18.18
Human Site: Y108 Identified Species: 50
UniProt: P10415 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10415 NP_000624.2 239 26266 Y108 G D D F S R R Y R R D F A E M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095818 249 26641 Y110 G D D F S R R Y R R D F A E M
Dog Lupus familis XP_858876 323 35928 Q123 E P L V G Q V Q E W M V A Y L
Cat Felis silvestris
Mouse Mus musculus P10417 236 26407 Y105 G D D F S R R Y R R D F A E M
Rat Rattus norvegicus P49950 236 26604 Y105 G D D F S R R Y R R D F A E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512467 195 20886 Q79 V T P G S A Q Q R F T Q V S D
Chicken Gallus gallus Q00709 233 25669 Y102 G D E F S R R Y Q R D F A Q M
Frog Xenopus laevis Q91827 228 25050 I103 F S E I S T Q I H V T P G T A
Zebra Danio Brachydanio rerio XP_001341214 209 23415 S92 S K Q L H V T S I T A H Q R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 79.9 20.7 N.A. 89.9 89.1 N.A. 39.3 74 37.2 44.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 82.3 31.5 N.A. 91.2 90.3 N.A. 55.2 78.6 54.3 60.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 13.3 80 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. 20 100 20 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 0 0 0 0 12 0 67 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 56 45 0 0 0 0 0 0 0 56 0 0 0 12 % D
% Glu: 12 0 23 0 0 0 0 0 12 0 0 0 0 45 0 % E
% Phe: 12 0 0 56 0 0 0 0 0 12 0 56 0 0 12 % F
% Gly: 56 0 0 12 12 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 12 0 0 0 12 0 0 12 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 12 12 0 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 56 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 12 0 0 0 0 0 0 0 0 12 0 0 0 % P
% Gln: 0 0 12 0 0 12 23 23 12 0 0 12 12 12 0 % Q
% Arg: 0 0 0 0 0 56 56 0 56 56 0 0 0 12 0 % R
% Ser: 12 12 0 0 78 0 0 12 0 0 0 0 0 12 0 % S
% Thr: 0 12 0 0 0 12 12 0 0 12 23 0 0 12 0 % T
% Val: 12 0 0 12 0 12 12 0 0 12 0 12 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 56 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _